In general, these charitable donations will not be deductible on your U.S. tax return. To be deductible, charitable donations need to be made to qualified organizations. A qualified organization is generally one that has received 501(c)(3) status from the IRS. If you are unsure, you can ask any organization whether it is a qualified organization, and most will be able to tell you. Or you can use the tool here to search for qualified organizations.